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. 2019 Jul 24;24(15):2678. doi: 10.3390/molecules24152678

Table 1.

Neuroprotective effect of Gaba.

STT Source Dose, Model Time of Treatment/Administration Effect Ref.
1 Kimchi-derived Lactobacillus buchneri 100 µg/mL, neuronal cells 24 h Preventing neurotoxic-induced cell death [13]
2 Lactobacillus plantarum-fermented chickpea milk 537.23 mg/L, PC12 cells 30 min Preventing MnCl2-induced injury [14]
3 Gaba receptor agonist Muscimol (1 mg/kg) and baclofen (20 mg/kg), rat 30 min Preventing brain ischemic injury and decreasing apoptosis [15,17]
4 Gaba receptor agonist Baclofen (10 mL/kg), rat Once daily/five weeks Alleviating neuronal damage and suppressing cytodestructive autophagy [16]