Table 1.
Neuroprotective effect of Gaba.
STT | Source | Dose, Model | Time of Treatment/Administration | Effect | Ref. |
---|---|---|---|---|---|
1 | Kimchi-derived Lactobacillus buchneri | 100 µg/mL, neuronal cells | 24 h | Preventing neurotoxic-induced cell death | [13] |
2 | Lactobacillus plantarum-fermented chickpea milk | 537.23 mg/L, PC12 cells | 30 min | Preventing MnCl2-induced injury | [14] |
3 | Gaba receptor agonist | Muscimol (1 mg/kg) and baclofen (20 mg/kg), rat | 30 min | Preventing brain ischemic injury and decreasing apoptosis | [15,17] |
4 | Gaba receptor agonist | Baclofen (10 mL/kg), rat | Once daily/five weeks | Alleviating neuronal damage and suppressing cytodestructive autophagy | [16] |