Table 1.

Surgical methods used to induce hind limb ischemia, time course of blood reperfusion recovery, whether the method is suitable to assess arteriogenesis and angiogenesis, and if arteriogenesis takes place, where it will take place.

Surgical Method Used to Induce HLI	Time Course of Blood Reperfusion (Days)	Ischemia Rate	Suitable to Studying Arteriogenesis?	Which Collateral Group Can Be Studied?	Suitable to Studying Angiogenesis in Calf Muscle?
Electrocoagulation of common iliac artery	7–14 days	moderate	Yes	Medial thigh muscles (includes adductor muscles) Quadriceps femoris Biceps femoris	Yes
Electrocoagulation of the femoral artery, distal from origin of deep branch	7–14 days	mild	Yes	Adductor muscles Quadriceps femoris Biceps femoris	Yes
Electrocoagulation of the femoral artery, proximal from origin of deep branch	7–14 days	mild	Yes	Quadriceps femoris Biceps femoris
Total excision of the femoral artery	28 days	severe	No		Yes
Double electrocoagulation of iliac and femoral artery	28 days	moderate	Yes	Medial thigh muscles (includes adductor muscles) Quadriceps femoris Biceps femoris	Yes
Ameriod constrictors		mild	Unclear		No