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. 2019 Jul 31;24(15):2786. doi: 10.3390/molecules24152786

Table 2.

(h)5-HT4(a) pharmacological profile of RS67333 and compound 19. 5-HT was used as a control 5-HT4R agonist.

Compound Log(EC50) 1 % Control Agonist Response 2 Profile
RS67333 −8.8 ± 0.2 48.7 ± 5.2 Partial agonist
19 −9.90 ± 0.0 59.0 ± 3.9 Partial agonist

1 Log(EC50) values are expressed as mean ± standard error of the mean (SEM) of at least two (RS67333) or three experiments (19); 2 % Control agonist response values are expressed as mean ± standard error of the mean (SEM) of at least two experiments.