Table 2.
BBB permeability of EGCG metabolites.
Sample | Permeability Coefficient (10−6cm s−1) | BBB Permeability (%) (30 min) |
---|---|---|
EGCG | 13.45 ± 0.57 | 4.00 ± 0.17 |
EGC | 16.70 ± 1.86 | 4.96 ± 0.55 |
GA | 31.73 ± 3.39 | 9.42 ± 1.01 |
EGC-M5 | 17.99 ± 0.79 | 5.34 ± 0.23 |
EGC-M5-GlcUA | 12.53 ± 0.02 | 3.72 ± 0.01 |
EGC-M5-Sul | 14.61 ± 1.35 | 4.34 ± 0.40 |
PG | 13.79 ± 1.62 | 4.10 ± 0.48 |
PG-GlcUA | 9.28 ± 1.41 | 2.76 ± 0.42 |
Data are expressed as the mean ± SEM (n = 3) [43]. (Data of Ref. 43 are modified).