Table 4.
Effects of ASC-secreted Extracellular Vesicles on Wound Healing: In vivo studies.
| ASC Source | Model | Effect | Reference |
|---|---|---|---|
| Human subcutaneous adipose tissue obtained from healthy females (18–35 years old). | Mouse full-thickness skin wound model | Acceleration of wound repair. | [74] |
| Human subcutaneous adipose tissue obtained after liposuction surgery (mean age of the patients: 20 ± 1.5 years). | Mouse full-thickness skin wound model | Increased number of blood vessels. Acceleration of wound repair. |
[78] |
| Human subcutaneous adipose tissue obtained by liposuction. | Rat excisional wound-splinting model. | Acceleration of wound repair. | [76] |
| Human subcutaneous adipose tissue. | Mouse full-thickness skin wound model | Acceleration of wound repair. Increased collagen deposition. Increased neovascularization and cell proliferation. |
[79] |