Table 2.
Demographic and clinical characteristics by cognitive impairment status.
|
Cognitively impaired (n = 13) |
Cognitively normal (n = 11) |
p-value | |
|---|---|---|---|
| Age (years) | 69.8 (5.9) | 73.1 (4.9) | 0.15 |
| Sex (% female) | 38.5% | 45.5% | 0.73 |
| Education (years) | 15.0 (2.6) | 16.6 (1.7) | 0.09 |
| Neurological diagnosis | |||
| PD | 10 | 8 | |
| PSP | 2 | 3 | |
| MSA | 1 | 0 | |
| Disease duration (years) | 8.3 (5.7) | 10.1 (11.5) | 0.63 |
| UPDRS Part III score | 28.2 (11.4) | 29.9 (12.4) | 0.73 |
| Presence of dyskinesia (% with) | 15.4% | 18.1% | 0.87 |
| Medication use (% taking) | |||
| Amantadine | 15.4% | 18.2% | 0.87 |
| MAO-B Inhibitor | 30.8% | 36.4% | 0.48 |
| Trihexiphenidyl | 7.7% | 0% | 0.35 |
| Donepezil | 30.8% | 0% | 0.04 |
| Presence of DBS (% with) | 30.8% | 9.1% | 0.14 |
| NPC (in cm) | 18.4 (4.3) | 12.5 (4.3) | 0.003 |
| Symptomatic CI | 61.5% | 81.8% | 0.23 |
| Subjective cognitive complaints (% reporting) | 92.3% | 54.5% | 0.03 |
| Total SAGE score (max 22) | 14.1 (3.6) | 19.5 (4.9) | 0.006 |
Data presented as mean (SD) unless otherwise noted. CI, convergence insufficiency; PD, Parkinson's disease; PSP, Progressive supranuclear palsy; MSA, Multiple system atrophy; UPDRS, Unified Parkinson's Disease Rating Scale; DBS, Deep brain stimulation; NPC, Near point of convergence; SAGE, Self-Administered Gerocognitive Exam. Bold values indicates p < 0.05.