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. 2019 Aug 13;12:2516865719867090. doi: 10.1177/2516865719867090

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — (A) Quantile-quantile plot and (B) Manhattan plot for epigenome-wide results testing for DNA methylation differences before, during, and after pregnancy in the Born into Life cohort (n = 21). (B) A total of 196 CpGs exhibit significant trend in DNA methylation measured in peripheral whole blood sampled at 4 occasions (once before, twice during, and once after pregnancy). The x-axis displays the chromosome on which the CpG is located, and the y-axis displays −log₁₀ (P value). The solid and dashed horizontal lines represent the Bonferroni-adjusted and FDR P value thresholds, respectively. FDR indicates false discovery rate.