Table 4.
Univariate analysis for risk factors of treatment failure.
| Variable | OR (95% CI) | p-value |
|---|---|---|
| Medication class | – | – |
| Penicillin VK | 1.429 (0.259–7.897) | 0.683 |
| Aminopenicillins | 0.643 (0.25–1.654) | 0.360 |
| Cephalosporins | 2.063 (0.715–5.947) | 0.180 |
| Fluoroquinolones | 0.285 (0.035–2.335) | 0.242 |
| SMX/TMP | N/A* | N/A* |
| Clindamycin | 0.864 (0.092–8.129) | 0.898 |
| Doxycycline | N/A* | N/A* |
| Linezolid | N/A* | N/A* |
| Metronidazole | 1.429 (0.259–7.897) | 0.683 |
| Organism | – | – |
| Streptococcus species | 1.281 (0.423–3.884) | 0.661 |
| Enterococcus species | 0.857 (0.169–4.348) | 0.852 |
| Peptostreptococcus species | 1.175 (0.221–6.253) | 0.850 |
| Clostridium species | 0.474 (0.055–4.065) | 0.496 |
| Source | – | – |
| Urinary | 1.565 (0.371–6.605) | 0.542 |
| Pulmonary | 0.577 (0.193–1.726) | 0.325 |
| Intra-abdominal | 0.993 (0.192–5.144) | 0.994 |
| Skin/Soft Tissue | 1.204 (0.385–3.759) | 0.750 |
| Other | N/A* | 0.968 |
| Unknown | 1.75 (0.616–4.969) | 0.293 |
| Length of hospital stay ⩾5 versus <5 days | 6.852 (0.865–54.249) | 0.068 |
| Bacteriostatic vs bactericidal | 1.429 (0.259–7.897) | 0.683 |
| Bioavailability high vs low | 0.78 (0.257–2.366) | 0.661 |
| Blood culture clearance yes versus no | 0.712 (0.255–1.987) | 0.517 |
*
Unable to be calculated due to small sample size
SMX/TMP, sulfamethoxazole/trimethoprim.