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. 2019 Aug 9;10:707. doi: 10.3389/fgene.2019.00707

Table 1.

Candidate autism spectrum disorder (ASD) target genes that showed significant differential expression in both microarray and RNA-seq datasets.

ASD SNP Target gene eQTL P-value Microarray P-value RNA-seq P-value
rs75782365 HIST1H1C 0.0015 0.0316 0.0228
rs3132581 HSPA1B 0.0058 0.0121 0.00299
rs11587682 PRPF3 0.017 0.0145 0.0325
rs4905226 SERPINA3 0.014 0.0376 0.00629

SNP, single nucleotide polymorphism; Target Gene, candidate target gene identified for each ASD GWAS locus; eQTL P-value, P-value of correlation between gene expression level and GWAS SNP genotype in GTEx database or Braineac database; Microarray P-value, P-value of the differentially expressed gene in microarray meta-analysis; RNA-seq P-value, P-value of the differentially expressed gene in RNA-seq analysis.