Table 3.
Results of the biochemical analysis of HFD/streptozotocin (STZ)-induced diabetic mice.
| NC | HFD/STZ | HFD/STZ+CaD | |
|---|---|---|---|
| BW (g) | 23.49 ± 1.78 | 28.37 ± 2.07* | 26.61 ± 1.37* |
| FBG (mmol/L) | 6.37 ± 1.44 | 20.51 ± 3.44* | 19.90 ± 5.33* |
| KW/BW (mg/g) | 6.19 ± 0.51 | 7.79 ± 0.51* | 6.41 ± 0.35# |
| UAE (µg/24 h) | 0.01 ± 0.01 | 2.13 ± 0.30* | 0.37 ± 0.31# |
| ALT (U/L) | 23.81 ± 8.79 | 49.20 ± 2.10* | 52.49 ± 3.01* |
| TG (mmol/L) | 0.67 ± 0.31 | 3.13 ± 0.08* | 3.04 ± 0.13* |
| TC (mmol/L) | 1.49 ± 0.29 | 3.92 ± 1.15* | 3.99 ± 0.80* |
| Scr (mmol/L) | 11.51 ± 1.62 | 13.10 ± 3.01 | 12.79 ± 2.45 |
BW, body weight; FBG, fasting blood glucose; KW/BW, kidney weight to body weight; UAE, urinary albumin excretion; ALT, alanine aminotransferase; TG, total triglycerides; TC, total cholesterol; Scr, serum creatinine; NC, normal control, n = 15; HFD/STZ, high-fat diet- and streptozotocin-treated, n = 15; CaD, calcium dobesilate, n = 15. *p < 0.05 vs. NC group; #p < 0.05 vs. HFD/STZ group.