Table 3.
Geometric mean daily macronutrient intake during 12 months of follow‐up and differences in intake in children assigned to LNS or control (intent to treat)
| Macronutrient | Baseline | 3 months | 6 months | 9 months | 12 months | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Control (n = 138) | LNS (n = 160) | Control (n = 128) | LNS (n = 149) | Control (n = 127) | LNS (n = 150) | Control (n = 122) | LNS (n = 128) | Control (n = 111) | LNS (n = 129) | |
| Energy (kcal) | ||||||||||
| Geometric mean | 311.2 (256.1, 378.1) | 238.8 (198.9, 286.7) | 461.4 (403.3, 527.8) | 594.5 (515.4, 685.8) | 681.5 (613.1, 757.4) | 788.5 (704.0, 883.1) | 754.0 (683.9, 831.4) | 833.9 (762.5, 911.9) | 963.6 (883.4, 1050.9) | 1080.9 (1001.8, 1166.3) |
| Difference in mean log energy† | – | −0.23* | – | 0.50*** | – | 0.38*** | – | 0.28** | – | 0.34** |
| Total fat (g) | ||||||||||
| Geometric mean | 9.2 (7.5, 11.4) | 6.8 (5.7, 8.2) | 14.3 (12.2, 16.7) | 22.9 (19.7, 26.7) | 22.5 (19.8, 25.5) | 31.8 (27.8, 36.3) | 25.2 (22.4, 28.4) | 34.4 (30.9, 38.2) | 31.3 (28.1, 35.0) | 40.4 (36.9, 44.1) |
| Difference in mean log fat† | – | −0.28* | – | 0.74*** | – | 0.61*** | – | 0.50*** | – | 0.50*** |
| Total carbohydrates (g) | ||||||||||
| Geometric mean | 47.6 (39.0, 58.1) | 37.2 (30.6, 45.3) | 71.1 (62.2, 81.4) | 82.2 (71.0, 95.3) | 99.2 (89.6, 109.9) | 102.2 (91.6, 113.9) | 110.5 (100.4, 121.6) | 108.3 (98.9, 118.6) | 141.8 (129.6, 155.2) | 148.9 (136.8, 162.0) |
| Difference in mean log carbohydrates† | – | −0.21* | – | 0.37** | – | 0.24* | – | 0.15 | – | 0.26* |
| Total protein (g) | ||||||||||
| Geometric mean | 8.1 (6.5, 10.1) | 6.0 (4.9, 7.3) | 12.8 (11.0, 14.9) | 15.6 (13.4, 18.2) | 21.7 (19.4, 24.4) | 24.4 (21.6, 27.6) | 23.0 (20.5, 25.9) | 24.0 (21.7, 26.5) | 29.5 (26.7, 32.7) | 31.7 (28.9, 34.7) |
| Difference in mean log protein† | – | −0.27* | – | 0.47*** | – | 0.39** | – | 0.25* | – | 0.30* |
LNS, lipid‐based nutrient supplements. Values are geometric means (95% confidence intervals). *P < 0.05; **P < 0.01; ***P < 0.001. †Differences in mean values and P‐values for the differences were obtained from longitudinal mixed models accounting for clustering at the village and individual levels and controlling for age, breastfeeding status and season. P‐values at baseline indicate the difference between study arms at that time point. P‐values for later visits compare the difference between study arms in change from baseline to that time point.