FIG 5.

Protein structure of substrate binding to Dac and the key site of interaction with substrate and substrate entrance sites in Dac. (a) The structure of protein (Dac) and the substrate (GlcNAc) binding to Dac of the inside active pocket. The substrate entrance was located in the center of Dac. (b) The interaction between critical residues and substrate. Green sticks show the hydrogen bonds between R157/R156 residues and GlcNAc. (c) The substrate entrance sites in Dac and distance of key residues from substrate.