Table 4 |.
Glucose levels (mg/dl) at time 0 in ITT and GTT
| Experimental group | Nondiabetic mice | Diabetic Akita mice |
|---|---|---|
| ITT TRPC6+/+ mice | 129 ± 5 (n = 6) | 476 ± 10a (n = 6) |
| ITT TRPC6−/− mice | 136 ± 9 (n = 6) | 485 ± 18.6b (n = 9) |
| GTT TRPC6+/+ mice | 129 ± 10 (n = 6) | 407 ± 15a (n = 6) |
| GTT TRPC6−/− mice | 136 ± 7 (n = 7) | 406 ± 20b (n = 7) |
GTT, glucose tolerance test; ITT, insulin tolerance test; n, number of mice in each group; WT, wild type.
a
P < 0.01 versus TRPC6+/+ WT mice.
b
P < 0.01 versus TRPC6−/− WT mice.