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. 2019 Aug 9;10:1862. doi: 10.3389/fimmu.2019.01862

Table 5.

Phase II and III clinical trials studying Jak inhibitors in alopecia areata and vitiligo.

Disease Drug name Identifier Status Phase, administration Enrollment Duration
Alopecia areata Baricitinib NCT03570749 Ongoing II/III, per os 725 36-week
PF-06651600 and PF-06700841 NCT02974868 Ongoing IIa, per os 142 24-week with extension period up to 2 years
Delgocitinib NCT02561585 Results submitted II, topical 31 12-week
Vitiligo Ruxolitinib NCT03099304 Ongoing II, topical 157 1-year with 1 year open-label extension
PF-06651600 and PF06700841 NCT03715829 Recruiting IIb, per os 330 60-week with 24 weeks dose ranging and 24 week extension period