Table 5.
Phase II and III clinical trials studying Jak inhibitors in alopecia areata and vitiligo.
Disease | Drug name | Identifier | Status | Phase, administration | Enrollment | Duration |
---|---|---|---|---|---|---|
Alopecia areata | Baricitinib | NCT03570749 | Ongoing | II/III, per os | 725 | 36-week |
PF-06651600 and PF-06700841 | NCT02974868 | Ongoing | IIa, per os | 142 | 24-week with extension period up to 2 years | |
Delgocitinib | NCT02561585 | Results submitted | II, topical | 31 | 12-week | |
Vitiligo | Ruxolitinib | NCT03099304 | Ongoing | II, topical | 157 | 1-year with 1 year open-label extension |
PF-06651600 and PF06700841 | NCT03715829 | Recruiting | IIb, per os | 330 | 60-week with 24 weeks dose ranging and 24 week extension period |