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. 2019 Jul 9;13(4):041501. doi: 10.1063/1.5096030

FIG. 5.

FIG. 5.

Paperfluidic fabrication methods. (a) Cartoon illustrating method for fabricating cutout paperfluidic devices. A computer-controlled razor blade (i.e., craft cutter) cuts the channel design out of a paper substrate resulting in a paperfluidic device. (b) One-step plotting of paperfluidic devices with a (hydrophobic) permanent marker, template, and paper substrate. Reproduced with permission from Nie et al., Anal. Chem. 84(15), 6331–6335 (2012). Copyright 2012 American Chemical Society. (c) Method for impregnating paper with wax using parafilm and a laminator. The channel design is cut out of the parafilm, matted to the paper substrate, and passed through a laminator. The result is paper with impregnated hydrophobic barriers from the parafilm wax. The process can be repeated several times to create a multilayer device. Reproduced with permission from Koesdjojo et al., J. Chem. Educ. 92(4), 737–741 (2015). Copyright 2015 American Chemical Society.