TABLE II.

Linear Regression Modeling of Natural Log Plasma Orexin A Levels in Prader-Willi Syndrome and Healthy Unrelated Sibling Control Children

	F-value	P-value
Model 1: Total sample
Diagnosis	14.1 (df = 1)	0.001*
Gender	0.18 (df = 1)	0.68
Age	0.06 (df = 1)	0.81
Overall model fit (R2 = 0.27)	4.8 (df = 3.37)	0.01*
Model 2: Female subjects
Diagnosis	4.9 (df = 1)	0.04*
Age	4.6 (df = 1)	0.05*
Overall model fit (R2 = 0.39)	4.8 (df = 2.15)	0.03*
Model 3: Male subjects
Diagnosis	10.9 (df = 1)	0.004*
Age	1.5 (df = 1)	0.23
Total fat	0.18 (df = 1)	0.68
Overall model fit (R2 = 0.40)	4.2 (df = 3.19)	0.02*

^*Indicated statistical significance for controlled linear regression analysis at P< 0.05 level of alpha.