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. Author manuscript; available in PMC: 2019 Aug 16.
Published in final edited form as: Eur J Nutr. 2015 Jun 29;55(4):1515–1524. doi: 10.1007/s00394-015-0969-z

Table 4.

Relations of three LCD scores to CMRF-INTERLIPID Study, Japan

Outcome variables Log CRP HDLc LDLc TC UA HbA1c

Usual LCD score
 Model 1
  β −0.008 ± 0.005 0.905 ± 0.146 −0.547 ± 0.310 0.511 ± 0.329 0.010 ± 0.011 0.004 ± 0.006
  P 0.079 <0.001 0.078 0.121 0.385 0.524
 Model 2
  β −0.005 ± 0.005 0.731 ± 0.144 −0.359 ± 0.315 0.496 ± 0.336 0.002 ± 0.012 0.004 ± 0.006
  P 0.240 <0.001 0.255 0.141 0.864 0.499
Animal-based LCD score
 Model 1
  β −0.006 ± 0.005 0.940 ± 0.148 −0.452 ± 0.316 0.669 ± 0.335 0.009 ± 0.012 0.007 ± 0.006
  P 0.232 <0.001 0.153 0.046 0.456 0.248
 Model 2
  β −0.003 ± 0.005 0.702 ± 0.148 −0.206 ± 0.324 0.634 ± 0.345 −0.002 ± 0.012 0.007 ± 0.007
  P 0.502 <0.001 0.525 0.067 0.900 0.307
Plant-based LCD score
 Model 1
  β −0.013 ± 0.004 0.678 ± 0.142 −0.474 ± 0.300 0.031 ± 0.319 −0.004 ± 0.011 −0.002 ± 0.006
  P 0.003 <0.001 0.114 0.922 0.709 0.754
 Model 2
  β −0.010 ± 0.004 0.648 ± 0.148 −0.405 ± 0.303 0.066 ± 0.323 −0.008 ± 0.011 −0.00002 ± 0.006
  P 0.018 <0.001 0.181 0.838 0.483 0.997

Coefficients (β) ± standard errors, and P values from multiple linear regression models used to examine relations of deciles of the three LCD scores to CMRF are shown. Model 1 included site, age, sex, and BMI; Model 2, Model 1 variables + smoking (cigarettes/day), and alcohol intake (% kcal), the Framingham physical activity score, and years of education (≤9, 10–12, 13–15, ≥16 year; ≤9 year as reference)

Italic values indicate statistical significance at the 5 % level

LCD low-carbohydrate diet, CMRF cardiometabolic risk factors, BMI body mass index, LDLc serum low-density lipoprotein cholesterol concentration, HDLc serum high-density lipoprotein cholesterol concentration, TC serum total cholesterol concentration, UA serum uric acid concentration, CRP C-reactive protein, HbA1c hemoglobin A1c