Table 4.
The relationship of BPE to CD44+/CD24−, TGFβ, ERα and PR in pre-menopausal patients
| Variable | Category | BPE |
ra | pa | |||
|---|---|---|---|---|---|---|---|
| Min (n = 12) | Mild (n = 14) | Mod (n = 13) | Marked (n = 9) | ||||
| CD44+/CD24−b | − | 9 (75%) | 5 (36%) | 7 (54%) | 4 (44%) | 0.15 | 0.30 |
| + | 3 (25%) | 9 (64%) | 6 (46%) | 5 (56%) | |||
| TGFβb | − | 10 (83%) | 12 (86%) | 13 (100%) | 7 (78%) | −0.03 | 0.82 |
| + | 2 (17%) | 2 (14%) | 0 (0%) | 2 (22%) | |||
| ERαc | < 5 | 5 (42%) | 5 (36%) | 4 (31%) | 3 (33%) | 0.11 | 0.46 |
| 5− | 6 (50%) | 8 (57%) | 8 (62%) | 5 (56%) | |||
| 10− | 0 (0%) | 1 (7%) | 1 (8%) | 1 (11%) | |||
| 20− | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| 30+ | 1 (8%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| PRc | < 5 | 9 (75%) | 11 (79%) | 5 (38%) | 5 (56%) | 0.14 | 0.36 |
| 5− | 2 (17%) | 2 (14%) | 6 (46%) | 3 (33%) | |||
| 10− | 0 (0%) | 1 (7%) | 2 (15%) | 1 (11%) | |||
| 20− | 1 (8%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| 30+ | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
BPE measurement made by JSS
a
Non-parametric Spearman correlation (r) and associated significance level (p)
b
Membranous staining of TDLU epithelial cells
c
% nuclear staining of TDLU epithelial cells