Table 5.
The relationship of BPE to CD44+/CD24−,TGFβ, ERα, and PR in post-menopausal patients
| Variable | Category | BPE |
ra | pa | |||
|---|---|---|---|---|---|---|---|
| Min (n = 11) | Mild (n = 12) | Mod (n = 6) | Marked (n = 3) | ||||
| CD44+/CD24−b | − | 3 (27%) | 4 (33%) | 2 (33%) | 0 (0%) | − 0.06 | 0.75 |
| + | 8 (73%) | 8 (67%) | 4 (67%) | 3 (100%) | |||
| TGFβb | − | 1 (9%) | 1 (8%) | 1 (17%) | 0 (0%) | − 0.01 | 0.97 |
| + | 10 (91%) | 11 (92%) | 5 (83%) | 3 (100%) | |||
| ERαc | < 5 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0.10 | 0.59 |
| 5− | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| 10− | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| 20− | 5 (45%) | 5 (42%) | 1 (17%) | 1 (33%) | |||
| 30+ | 6 (55%) | 7 (58%) | 5 (83%) | 2 (67%) | |||
| PRc | < 5 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0.10 | 0.57 |
| 5− | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |||
| 10− | 2 (18%) | 1 (8%) | 0 (0%) | 0 (0%) | |||
| 20− | 5 (45%) | 9 (75%) | 4 (67%) | 2 (67%) | |||
| 30+ | 4 (36%) | 2 (17%) | 2 (33%) | 1 (33%) | |||
BPE measurement made by JSS
a
Non-parametric Spearman correlation (r) and associated significance level (p)
b
Membranous staining of TDLU epithelial cells
c
% nuclear staining of TDLU epithelial cells