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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Mutat Res Genet Toxicol Environ Mutagen. 2019 Jan 18;839:21–35. doi: 10.1016/j.mrgentox.2019.01.007

Table 4:

Comparison of TGR and comet assay results using the WoE approach

A: Liver Data
Liver   TGR mutation (Mice and/or Rats)
Result + Total
Comet
(Mice and/or Rats)
+ 23 4 27
3 5 8
  Total 26 9 35
B: GI Tract Data
GI tract    TGR mutation (Mice and/or Rats)
Result + Total
Comet
(Mice and/or Rats)
+ 14 3 17
0 2 2
  Total 14 5 19
C: Bone Marrow Data
Bone marrow TGR mutation (Mice and/or Rats)
Result + Total
Comet
(Mice and/or Rats)
+ 7 1 8
5 2 7
Total 12 3 15