. Author manuscript; available in PMC: 2020 Mar 1.

Published in final edited form as: Mutat Res Genet Toxicol Environ Mutagen. 2019 Jan 18;839:21–35. doi: 10.1016/j.mrgentox.2019.01.007

Table 5:

Statistical analyses of results for liver, GI tract and bone marrow (WoE approach)

Tissue	Sensitivity^# (95% CI)	PI	BI	Kappa (95% CI)	PABAK (95% CI)	AC1 (95% CI)
Liver	0.82 (0.70-0.97)	0.51	0.03	0.46^c (0.13^e-0.79)	0.60^c (0.31^d-0.83)	0.68^b (0.44^c-0.93)
GI tract	1.00 (0.75-1.00)	0.63	0.16	0.50^c (0.11^e-0.88)	0.68^b (0.37^d-1.00)	0.77^b (0.49^c-1.00)
Bone marrow	0.58 (0.32-0.81)	0.33	−0.27	0.17^e (−0.25^g-0.59)	0.20^e (−0.33^g-0.73)	0.28^d (−0.29^g-0.85)

= ability of the comet assay to detect TGR positives

PI = prevalence index

BI = bias index

CI = confidence interval

= very good agreement (0.81-1.00)

= good agreement (0.61-0.80)

= moderate agreement (0.41-0.60)

= fair agreement (0.21-0.40)

= poor agreement (<0.20)

= fair disagreement (−0.21 to −0.40)