Table 9:

A comparison of statistical analyses for liver, stomach and bone marrow after data curation

A: Liver
Table	Sensitivity# (95% CI)	PI	BI	Kappa (95% CI)	PABAK (95% CI)	AC1 (95% CI)
+ve and −ve	0.86 (0.72-0.99)	0.61	0.09	0.53c (0.20e−0.85)	0.70b (0.45c-0.86)	0.78b (0.57c-0.99)
E calls +ve	0.86 (0.74-0.97)	0.64	0.07	0.44c (0.14e −0.73)	0.67b (0.43c-0.86)	0.76b (0.58c-0.95)
E calls −ve	0.69 (0.53-0.84)	0.43	0.24	0.35d (0.09e −0.60)	0.43c (0.14e −.71)	0.51c (0.24d-0.79)
B: Stomach
Table	Sensitivity# (95% CI)	PI	BI	Kappa (95% CI)	PABAK (95% CI)	AC1 (95% CI)
+ve and −ve	0.80 (0.35-1.00)	0.80	0.20	NA	0.60c (−0.20f-1.00)	0.75b (0.03 e −1.00)
E calls +ve	0.57 (0.13-1.00)	0.57	0.43	NA	0.14e (−0.43h-0.71)	0.35d (−0.59h-1.00)
E calls −ve	1.00 (0.42*−1.00)	0.29	−0.14	0.70b (−0.01f-1.00)	0.71b (0.14e −1.00)	0.74b (0.11 e −1.00)
C: Colon
Table	Sensitivity# (95% CI)	PI	BI	Kappa (95% CI)	PABAK (95% CI)	AC1 (95% CI)
+ve and −ve	1.00 (0.63*−1.00)	1.00	0.00	NA	1.00a (0.63*b-1.00)	1.00a (0.63*b-1.00)
D: Bone Marrow
Table	Sensitivity# (95% CI)	PI	BI	Kappa (95% CI)	PABAK (95% CI)	AC1 (95% CI)
+ve and −ve	0.50 (0.14-0.86)	0.50	0.50	NA	0.00 f (−0.60h-0.60)	0.20 e (−0.60h-1.00)
E calls +ve	0.62 (0.31-0.92)	0.62	0.38	NA	0.23d (−0.23g-0.69)	0.44c (0.58h-0.95)
E calls −ve	0.38 (0.08-0.69)	0.39	0.62	NA	−0.23g (−0.69i-0.34)	−0.07 e (−0.80i-0.65)

^#= ability of the comet assay to detect TGR positives

^*= Clopper-Pearson Lower Limit

CI = confidence interval

PI = prevalence index

BI = bias index

^a= very good agreement (0.81-1.00)

^b= good agreement (0.61-0.80)

^c= moderate agreement (0.41-0.60)

^d= fair agreement (0.21-0.40)

^e= poor agreement (<0.20)

^f= some disagreement (0 to −0.20)

^g= fair disagreement (−0.21 to −0.40)

^h= moderate disagreement (−0.41 to −0.60)

ⁱ= substantial disagreement (−0.61 to −0.80)