Figure 7. Ubiquitin binds to Kog1 in response to temperature upshift.
A. Wild type yeast cells expressing KOG1-HA (Y985) and ubiquitin were subjected to heat stress for 1 hr. Cell extracts were precipitated with anti-HA antibody and the levels of Kog1-HA and ubiquitin in the cell extracts and precipitates were analyzed by western blotting. B. Wild type yeast cells expressing KOG1-HA (Y985), together with myc-tagged ubiquitin or ubiquitin G76A mutant were subjected to heat stress for 1 hr. Cell extracts were precipitated with anti-HA antibody and the levels of Kog1-HA and myc tagged ubiquitin in the extracts and precipitates were examined by western blotting.