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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: J Physiol. 2019 Jul 15;597(16):4325–4340. doi: 10.1113/JP278427

Figure 2. AT1 receptors and PKC activity are not actively involved in regulating presynaptic NMDAR activity in PVN presympathetic neurons in WKY rats.

Figure 2.

A–C, Original traces and cumulative probability plots show the effect of bath application of 50 μmol/L AP5 on the frequency and amplitude of mEPSCs of labeled PVN neurons pretreated with vehicle, 2 μmol/L losartan, or 1 μmol/L chelerythrine in brain slices from WKY rats. D and E, Summary data show the effects of losartan or chelerythrine on the frequency (D) and amplitude (E) of mEPSCs before and after AP5 bath application in labeled PVN neurons from SHRs (n = 10 neurons from 4 rats per group). LST, losartan; CLT, chelerythrine.