Table 4.

Rate of Respiratory Infectious Episodes (RIE) Between Visits (Average 3-Months) Reported by Those with ≥1 Negative Life Events (NLEs) Relative to Those with No NLE

Age of Child in Months	Recording Period of NLEs Relative to the 3-month Period of Recorded Child RIEs	Mother Negative Life Events				Child Negative Life Events
		RIE Rate Ratio	95% CI		p-value	RIE Rate Ratio	95% CI		p-value
3 – 27	Current NLEs+
	No NLE	1.00	ref	ref		1.00	ref	ref
	Yes, NLEs	1.02	1.00	1.05	0.07	1.08	1.04	1.12	<0.001
	Previous Year NLEs#
	No NLE	1.00	ref	ref		1.00	ref	ref
	Yes, NLEs	1.03	1.01	1.06	0.01	1.12	1.09	1.15	<0.001
27 – 48	Current NLEs+
	No NLE	1.00	ref	ref		1.00	ref	ref
	Yes, NLE	1.01	0.98	1.05	0.57	1.06	1.01	1.11	0.01
	Previous Year NLEs#
	No NLE	1.00	ref	ref		1.00	ref	ref
	Yes, NLEs	1.05	1.02	1.08	0.001	1.06	1.03	1.10	<0.001
	Early Life NLEs§
	No NLE	1.00	ref	ref		1.00	ref	ref
	Yes, NLEs	1.04	1.00	1.07	0.08	1.09	1.04	1.14	<0.001

Note: NLEs adjusted for all factors in table 1.

⁺Current NLEs: NLEs occurring in the same 3-month window for which RIEs were recorded;

^#Previous Year NLEs: NLEs occurring in the 12-month period prior to, but not including, the 3-month RIEs recording window (no NLE; ≥ 1 NLEs);

^§Early Life NLEs: for children > 27 months of age, NLEs occurring in the first 12 months of life