Table 2.
In vitro activities of carbapenems to 84 CREL isolates with or without carbapenemase.
| Antibiotics | Carbapenemase positive (n = 50) | Carbapenemase negative (n = 34) | *P | ||||||
|---|---|---|---|---|---|---|---|---|---|
| R% | MIC (μg/mL) | R% | MIC (μg/mL) | ||||||
| MIC range | MIC50 | MIC90 | MIC range | MIC50 | MIC90 | ||||
| IPM | 100 | 8–256 | 128 | 256 | 20.6 | 1–64 | 2 | 4 | P < 0.01 |
| MEM | 100 | 16–256 | 128 | 256 | 11.8 | 0.5–8 | 1 | 4 | P < 0.01 |
| ETP | 100 | 32–256 | 128 | 256 | 64.7 | 0.5–64 | 2 | 4 | P < 0.01 |
IPM, imipenem; MEM, meropenem; ETP, ertapenem. R, resistant.
*
P-value for comparisons of resistance rates between carbapenemase-positive and carbapenemase-negative groups.