Fig 3. Specific parameter sets.

(A) Importance of critical parameters sets. In the shown example, model state B is assumed to be achieved initially only from either state A or C. Therefore, the corresponding connections μ_AB and μ_CB are defined as a critical parameter set. Only models containing at least one of the parameters are evaluated. (B) Definition of swap parameter sets: The transition from A to B, μ_AB, as well as a multiplication within B, ρ_B, are structurally similar parameters that can explain an increase in model state B and define a swap parameter set, i.e., parameters can be replaced against each other for model testing.