Table 1. Background characteristics, lifestyle variables and variables relating to infertility and infertility treatment among the participants of the two cohorts.
| Characteristic | Lifestyle study N = 241 |
UppStART study N = 432 |
P-Value | ||
|---|---|---|---|---|---|
| Age (years), median (IQR) | 31.1 | (27.9–34.7) | 34.0 | (31.0–37.0) | <0.001 |
| Level of education, n (%) | <0.001 | ||||
| College/university | 153 | (64.3) | 334 | (78.8) | |
| Non-college/non-university | 85 | (35.7) | 90 | (21.2) | |
| Body Mass Index (BMI) in kg/m2, median (IQR) | 23.7 | (21.4–27.9) | 22.7 | (20.9–25.6) | <0.001 |
| Any alcohol consumption, n (%) | 165 | (69.0) | 337 | (78.0) | 0.013 |
| Smokinga, n (%) | 78 | (32.4) | 148 | (35.3) | 0.493 |
| Smokingb, n (%) | 23 | (9.5) | 14 | (3.3) | 0.002 |
| Caffeine- dailyc in mg/day, median (IQR) | 221.1 | (0.0–331.7) | 221.1 | (68.1–382.3) | <0.001 |
| Physical activity scored, median (IQR) | 1.7 | (1.7–1.8) | 1.7 | (1.6–1.8) | 0.064 |
| History of depression, n (%) | 42 | (17.6) | 58 | (13.4) | 0.183 |
| Cause of infertility, n (%) | 0.872 | ||||
| Mixed/Unknown | 133 | (55.2) | 88 | (54.0) | |
| Male | 44 | (18.3) | 28 | (17.2) | |
| Female | 64 | (26.6) | 47 | (28.8) | |
| Duration of infertility (years), median (IQR) | 2.0 | (1.5–3.0) | 2.0 | (2.0–3.0) | 0.020 |
| Total AFC, median (IQR) | 10.0 | (7.0–14.0) | 16.0 | (10.0–24.0) | <0.001 |
| Total AFC< 7, N (%) | 50 | (21.0) | 24 | (8.2) | <0.001 |
| AMH, median (IQR) | 2.5 | (1.6–4.7) | 2.1 | (1.1–3.8) | 0.008 |
| FSH- total dose for stimulation, median (IQR) | 1513.5 | (1198.5–2250.0) | 1650 | (1206.2–2610.0) | 0.119 |
| Number of aspirated oocytes, median (IQR) | 9.0 | (6.0–12.5) | 8.0 | (5.0–11.0) | 0.003 |
| Number of mature oocytes, median (IQR) | 7.0 | (5.0–11.0) | 7.0 | (4.0–11.0) | 0.142 |
| Number of embryos created, median (IQR) | 4.0 | (2.0–6.5) | 4.0 | (2.0–7.0) | 0.621 |
| Number of embryos used, median (IQR) | 2.0 | (1.0–4.0) | 2.0 | (1.0–4.0) | 0.495 |
a Smoking in general, currently or within the past year
b currently smoking only.
c 1 cup of coffee = 77mg caffeine
d Physical activity score based on validated scale and reflecting different levels of occupational and leisure activity