Table 2. Incidence rate ratio (IRR) and 95% Confidence intervals for number of aspirated oocytes and number of mature oocytes in relation to individual risk lifestyle factors in study cohorts.
| Lifestyle study cohort | UppStART study cohort | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Outcome | Variable | Crude IRR (CI)a | p-value | Adjusted IRR (CI)b | p-value | Crude IRR (CI)a | p-value | Adjusted IRR (CI)b | p-value |
|
Number of aspirated oocytes |
BMI | 0.98 (0.97,1.00)* | 0.019 | 0.98 (0.97, 1.00)* | 0.023 | 0.97 (0.95, 0.99)* | 0.008 | 0.97 (0.95, 0.99)* | 0.011 |
| Smoking | 0.81 (0.70, 0.94)* | 0.005 | 0.79 (0.68, 0.93)* | 0.004 | 0.99 (0.85, 1.16) | 0.914 | 1.01 (0.86, 1.19) | 0.865 | |
| Age | 1.00 (0.99, 1.01) | 0.994 | 1.00 (0.98, 1.01) | 0.893 | 0.98 (0.96, 0.99)* | 0.010 | 0.98 (0.96, 1.00)* | 0.017 | |
| Alcohol | 1.01 (0.87, 1.17) | 0.873 | 1.04 (0.89, 1.20) | 0.651 | 0.87 (0.73, 1.05) | 0.142 | 0.90 (0.75, 1.08) | 0.260 | |
| Caffeine | 1.00 (1.00, 1.00) | 0.384 | 1.00 (1.00, 1.00) | 0.885 | 1.00 (1.00, 1.00) | 0.579 | 1.00 (1.00, 1.00) | 0.978 | |
| Physical activity | 0.63 (0.31, 1.30) | 0.212 | 0.62 (0.31, 1.26) | 0.187 | 0.87 (0.50, 1.51) | 0.617 | 0.75 (0.43, 1.31) | 0.319 | |
| Depression | 1.13 (0.95, 1.34) | 0.179 | 1.15 (0.97, 1.36) | 0.099 | 0.88 (0.71, 1.09) | 0.246 | 0.91 (0.73, 1.12) | 0.364 | |
|
Number of mature oocytes |
BMI | 0.98 (0.96, 1.00)* | 0.019 | 0.98 (0.97, 1.00)* | 0.026 | 0.97 (0.95, 0.99)** | 0.018 | 0.97 (0.95, 0.99)* | 0.017 |
| Smoking | 0.81 (0.69, 0.94)* | 0.006 | 0.79 (0.67, 0.93)* | 0.004 | 1.01 (0.85, 1.18) | 0.983 | 1.02 (0.86, 1.20) | 0.743 | |
| Age | 1.00 (0.98, 1.01) | 0.947 | 1.00 (0.98, 1.01) | 0.753 | 0.98 (0.96, 0.99)* | 0.010 | 0.98 (0.96, 1.00)* | 0.022 | |
| Alcohol | 1.05 (0.90, 1.22) | 0.529 | 1.08 (0.92, 1.26) | 0.335 | 0.82 (0.69, 0.99)* | 0.035 | 0.84 (0.70, 1.01) | 0.067 | |
| Caffeine | 1.00 (1.00, 1.00) | 0.378 | 1.00 (1.00, 1.00) | 0.986 | 1.00 (1.00, 1.00) | 0.889 | 1.00 (1.00, 1.00) | 0.472 | |
| Physical activity | 0.71 (0.34, 1.49) | 0.365 | 0.75 (0.34, 1.47) | 0.351 | 0.81 (0.46, 1.44) | 0.474 | 0.70 (0.40, 1.22) | 0.207 | |
| Depression | 1.13 (0.94, 1.34) | 0.192 | 1.16 (0.97, 1.38) | 0.105 | 0.86 (0.69, 1.08) | 0.196 | 0.89 (0.71, 1.11) | 0.300 | |
a Incidence rate ratio + 95% CI for the crude univariable analysis
b Incidence rate ratio + 95% CI for the adjusted analysis (adjusted for age, BMI, smoking, alcohol consumption, daily caffeine consumption, physical activity score and history of depression)
* p<0.05