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FS14-NP/siIL-1β Downmodulate Inflammatory Cytokines in Arthritic Joints
Paws were isolated on day 9 and homogenized. The mRNA expression for (A) IL-1β, (C) TNF-α, (D) MMP-3, and (E) MMP-13 were measured by real-time PCR, relative to GAPDH. Paw lysates were collected, and the expression of the inflammatory cytokine (B) IL-1β was assayed by ELISA; *p < 0.05, ***p < 0.001.
