Skip to main content
. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Neuropharmacology. 2019 Jun 18;157:107669. doi: 10.1016/j.neuropharm.2019.107669

Figure 1: Nicotine drinking behavior in adult C57BL/6J mice.

Figure 1:

Mice were exposed to either water or nicotine (5 – 960 μg/ml) in two-bottle choice paradigm. Average of nicotine intake (mg/kg/day), preference (%) and total fluid intake (ml/day) over 3 days were calculated for each nicotine concentration in male and female C57BL/6J mice. Significant A) nicotine intake and B) preference were observed in female mice beginning from 60 μg/ml concentration of nicotine in comparison to male counterparts. C) Total fluid intake of both male and female was similar. Data are presented as the mean ± SEM of 10 animals. * indicates p < 0.05.