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. 2019 Aug 14;39(33):6540–6554. doi: 10.1523/JNEUROSCI.2831-18.2019

Table 5.

Brain regions with GMVs smaller in ASD and associated with RRB symptoms

Region Right/left Peak coordinate (MNI)
ASD vs TD Association with RRB symptoms (RRB = 0 vs RRB ≥ 1)
X Y Z t-value t-value p-value
Dataset collected at University of Utah
    Amygdala Right 30 −2 −20 4.7 0.64 0.53
    ACC Right 8 44 8 4.6 −0.84 0.41
    Anterior insula Right 36 22 0 4.2 0.75 0.46
    pSPL Right 32 −54 50 4.6 2.7 0.014
Dataset collected at ETH Zürich
    Hippocampus Right 26 −4 −22 4.2 0.39 0.71
    Anterior insula Right 36 14 −10 3.9 0.83 0.43
    pSPL Right 30 −52 58 4.1 2.8 0.022

t-values and p-values in “RRB = 0 vs RRB ≥ 1” indicate results of two-sample t test of GMVs between the ASD individuals with zero RRB scores and those with ≥1 RRB scores. Positive t-values denote that the GMVs were larger in individuals with zero RRB, whereas the negative values indicate that the GMVs were smaller.