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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Immunol Rev. 2019 Sep;291(1):134–153. doi: 10.1111/imr.12796

FIGURE 1. Proximal TCR Signaling, Adapters, and Secondary Messengers.

FIGURE 1.

Simplified scheme of the canonical pMHC/TCR signaling pathway viewed as a linear relay system from TCR to transcription factors through proximal kinases, adapters, second messengers, and effector kinase pathways.