Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Checkpoint blockade in the form of anti-CTLA4 or anti-PD1 as well as generation or CAR-T cells to fight tumors may lead to increased tonic mTORC1 signaling in T cells. Questions such as the impact of T cell therapy approaches on mTOR signaling in T cells will be important to address.
