Table 5. Results of the statistical analysis.
| Parameter | Measured variable | Odds ratio | CI (LL) a | CI (UL) b | p -Value |
|---|---|---|---|---|---|
| Age | Continuous variable | – | – | – | 0.0456 |
| Gender | Male:Female | 0.627 | 0.2511 | 1.5655 | 0.3147 |
| Pathology | Malignant tumor:ORN | 0.8553 | 0.2411 | 3.0344 | 0.8073 |
| ASA score | ASA1:ASA2 | 0.4236 | 0.0626 | 2.8687 | 0.5374 |
| ASA1:ASA3 | 0.3333 | 0.0419 | 2.6528 | 0.4225 | |
| ASA2:ASA3 | 0.7869 | 0.2262 | 2.7368 | 0.8918 | |
| Alcohol usage | Yes:No | 1.3511 | 0.4998 | 3.6527 | 0.5501 |
| Tobacco usage | Yes:No | 1.2082 | 0.3982 | 3.666 | 0.7364 |
| Defect type c | H:L | 2.2 | 0.3832 | 12.6309 | 0.7226 |
| H:LC | 2.6833 | 0.3618 | 19.9005 | 0.6517 | |
| H:LCL | 2.4267 | 0.3663 | 16.078 | 0.6929 | |
| H:Ma | 1.1667 | 0.0789 | 17.2616 | 0.9999 | |
| L:LC | 1.2197 | 0.1771 | 8.4023 | 0.9986 | |
| L:LCL | 1.103 | 0.1801 | 6.7573 | 0.9999 | |
| L:Ma | 0.5303 | 0.0378 | 7.4307 | 0.9635 | |
| LC:LCL | 0.9043 | 0.1152 | 7.0992 | 0.9999 | |
| LC:Ma | 0.4348 | 0.026 | 7.2647 | 0.9244 | |
| LCL:Ma | 0.4808 | 0.0311 | 7.4223 | 0.9464 | |
| Operation time | Continuous variable | – | – | – | 0.16 |
| Simultaneous flaps d | ALT:None | 1.3105 | 0.2402 | 7.1495 | 0.9242 |
| ALT:RFF | 0.45 | 0.0301 | 6.7347 | 0.7637 | |
| None:RFF | 0.3434 | 0.0352 | 3.3512 | 0.5076 | |
| Osteotomized segments | 1:2 | 1.125 | 0.3079 | 4.1099 | 0.9747 |
| 1:3 | 1.9459 | 0.3474 | 10.8988 | 0.6304 | |
| 2:3 | 1.7297 | 0.3018 | 9.9148 | 0.7372 | |
| Neck dissection e | None:Simultaneous | 0.6741 | 0.1998 | 2.274 | 0.7225 |
| None:Previous | 0.9074 | 0.1469 | 5.6063 | 0.9913 | |
| Simultaneous:Previous | 1.3462 | 0.2505 | 7.2346 | 0.9078 | |
| Tracheotomy | Yes:No | 0.6667 | 0.2289 | 1.9417 | 0.4544 |
| Chemotherapy | Post-op:Pre-op | 1.6 | 0.0762 | 33.5807 | 0.9245 |
| Post-op:Both | 0.8 | 0.0334 | 19.1359 | 0.9839 | |
| Pre-op:Both | 0.5 | 0.0098 | 25.4471 | 0.9027 | |
| Preoperative radiotherapy | Yes:No | 1.8462 | 0.5899 | 5.778 | 0.289 |
| Postoperative radiotherapy | Yes:No | 0.517 | 0.1651 | 1.6188 | 0.2543 |
Abbreviations: ALT, anterolateral thigh flap; ASA, American Society of Anesthesiologists score; ORN, osteoradionecrosis; RFF, radial forearm flap.
a
CI (LL): 95% confidence interval, lower limit.
b
CI (UL): 95% confidence interval, upper limit.
c
Defect classification according to Jewer et al. 10
d
Simultaneous flaps: additional free flaps used during fibula free flap procedure.
e
Neck dissection: either none, a previous or a simultaneous (during free flap surgery) neck dissection was recorded.