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. Author manuscript; available in PMC: 2020 Mar 14.
Published in final edited form as: J Phys Chem B. 2019 Mar 5;123(10):2217–2234. doi: 10.1021/acs.jpcb.8b10946

Table 12:

Convergence diagnostics for the three sampling algorithms applied to the Genetic toggle switch example

Parameter AMH-FSP ADAMH-FSP-Krylov Hybrid
Geweke IACT Geweke IACT Geweke IACT
log10(k0X) 1.00e+00 2.57e+01 1.00e+00 2.68e+01 1.00e+00 2.61e+01
log10(k1X) 1.00e+00 2.59e+01 1.00e+00 2.72e+01 1.00e+00 2.54e+01
log10(γX) 1.00e+00 2.56e+01 1.00e+00 2.69e+01 1.00e+00 2.60e+01
log10(k0Y ) 9.78e−01 2.79e+01 9.91e−01 2.70e+01 9.93e−01 2.85e+01
log10(k1Y ) 1.00e+00 2.65e+01 1.00e+00 2.64e+01 9.99e−01 2.47e+01
log10(γY ) 1.00e+00 2.64e+01 1.00e+00 2.62e+01 1.00e+00 2.46e+01

Geweke column shows the p-values in the Geweke diagnostics. This test is passed at 5% significance level if the p-value is above 0.05.

IACT column shows the integrated autocorrelation time, which is the number of samples in the MCMC chain that are equivalent to an independent posterior sample.