. Author manuscript; available in PMC: 2020 Mar 14.

Published in final edited form as: J Phys Chem B. 2019 Mar 5;123(10):2217–2234. doi: 10.1021/acs.jpcb.8b10946

Table 3:

Performance of the sampling algorithms on the Two-state gene expression example

	mESS	CPU time (sec)	$\frac{CPU time}{mESS} (\sec)$	Number of full evaluations	Number of rejections	Number of rejections by full FSP
AMH-FSP	6078.61	20319.33	3.34	100000	79152	79152
ADAMH-FSP-Krylov	5141.64	11243.99	2.19	18905	81193	98
Hybrid	5104.85	8226.57	1.61	2111	79378	7

Each algorithm was run for 10⁵ iterations.