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. Author manuscript; available in PMC: 2019 Aug 16.
Published in final edited form as: Nature. 2018 Jun 6;558(7708):73–79. doi: 10.1038/s41586-018-0175-2

Fig. 2. Missense variant rs28929474:T in SERPINA1 is a trans pQTL hotspot.

Fig. 2

Outermost numbers indicate chromosomes. Lines link the genomic location of rs28929474 with genes encoding significantly associated proteins. Associations with and without asterisks indicate significance at P < 5 × 10−8 and P < 1.5 × 10−11, respectively. Line thickness is proportional to effect size (red, positive; blue, negative); n = 3,301 participants.