Extended Data Fig. 2. Examples of protein targets for which the SOMAmer is highly specific.

SDS–PAGE with Alexa-647-labelled proteins captured by the IL1RL2 SOMAmer (a) or GP1BA SOMAmer (b). For each protein target, the protein captured by the SOMAmer is compared to the standard. The cognate targets are the only ones with protein visible in the capture lanes, whereas the proteins homologous to the target proteins show no evidence of binding. These experiments were performed once. MW markers, molecular weight markers.