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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: J Biomed Inform. 2019 Jun 22;96:103239. doi: 10.1016/j.jbi.2019.103239

Table 3.

Relationship types and classes involved in the relationship.

Plain English Description Concept 1 Class Relationship Type Concept 2 Class Axioms
Generic class hierarchy* (Multiple) Is a (Multiple) 2,214
Generic external mapping* (Multiple) Maps to (Multiple) 664
Evidence to support use (Multiple) Was studied in Study 18,076
Biomarker-specific disease subtype** BioCondition Is bio subclass Condition 21
Brand name(s)* Component Has brand name Brand Name 2,140
Drug prescription signetur Component Has sig Sig or Sig Stub 6,370
Drug route(s)* Component May have route Route 624
Year of FDA approval Component Was FDA approved yr Year 390
Middle author Reference Has middle author Author 68,288
First author Reference Has first author Author 5,507
Last author Reference Has last author Author 5,479
Journal of publication Reference Was published in Journal 5,642
PubMed URL Reference Has PMID PubMedURL 5,646
Reference title Reference Has title ReferenceTitle 5,653
Reference URL Reference Has URL ReferenceURL 5,693
Year of Publication Reference Was published year Year 5,457
Biomarker-specific regimen** Regimen Has bioaccepted use BioCondition 167
Antineoplastic interventions* Regimen Has antineoplastic Component 4,219
Supportive interventions* Regimen Has supportive med Component 1,258
Immune suppressing interventions* Regimen Has immunosuppressor Component 165
Local interventions, including CNS therapy* Regimen Has local therapy Component 134
Episode context of treatment* Regimen Has context Context 2,487
Disease context of treatment** Regimen Has accepted use Condition 4,087
Current Regimen** Regimen Is current in Condition 2,248
Historical Regimen** Regimen Is historical in Condition 368
Link to preceding treatment(s)** Regimen Can be preceded by Regimen or Regimen Stub 969
Link to subsequent treatment(s)** Regimen Can be followed by Regimen or Regimen Stub 868
Direct comparison within an RCT Regimen Has been compared to Regimen or Regimen Stub 3,872
Regimen type* Regimen Has regimen type Regimen type 1,688
Antineoplastic interventions (RxNorm)*+ Regimen Has antineopl Rx RxNorm Ingredient 4,018
Supportive interventions (RxNorm)*+ Regimen Has support med Rx RxNorm Ingredient 1,001
Immune suppressing interventions (RxNorm)*+ Regimen Has immunosuppr Rx RxNorm Ingredient 143
Local interventions, including CNS therapy (RxNorm)*+ Regimen Has local therap Rx RxNorm Ingredient 130
Reference Study Has reference Reference 5,648
Study group Study Has study group Study Group 1,147
Study’s short name Study Has study short name Study name short 4,787
Total relationships: 177,268
*

These relationship types are included in the first public OHDSI release

**

These relationship types will be included in the second public OHDSI release

+

These relationship types are named mapping relationships to external vocabularies