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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: J Biomed Inform. 2019 Jun 22;96:103239. doi: 10.1016/j.jbi.2019.103239

Table 4.

Example of the CapeOx regimen with its relationships. For readability, concept codes have been replaced with concept names. Not shown are 20 studies that evaluated CapeOx alone or as part of an RCT.

Concept 1 Relationship Type Concept 2 Vocab. 1 Vocab. 2
CapeOx Has regimen type Chemotherapy HemOnc HemOnc
CapeOx Has antineoplastic Capecitabine HemOnc HemOnc
CapeOx Has antineoplastic Oxaliplatin HemOnc HemOnc
CapeOx Has antineopl Rx (RxCUI) 194000 HemOnc RxNorm
CapeOx Has antineopl Rx (RxCUI) 32592 HemOnc RxNorm
CapeOx Has context Adjuvant therapy HemOnc HemOnc
CapeOx Has context Non-curative first-line therapy HemOnc HemOnc
CapeOx Has context Non-curative second-line therapy HemOnc HemOnc
CapeOx Has context Non-curative third-line therapy HemOnc HemOnc
CapeOx Has context Non-curative therapy HemOnc HemOnc
CapeOx Has context Neoadjuvant therapy HemOnc HemOnc
CapeOx Has indication Colon cancer HemOnc HemOnc
CapeOx Has indication Esophageal cancer HemOnc HemOnc
CapeOx Has indication Gastric cancer HemOnc HemOnc
CapeOx Has indication Hepatocellular carcinoma HemOnc HemOnc
CapeOx Has indication Pancreatic cancer HemOnc HemOnc
CapeOx Has indication Rectal cancer HemOnc HemOnc
CapeOx Is current in Colon cancer HemOnc HemOnc
CapeOx Is current in Esophageal cancer HemOnc HemOnc
CapeOx Is current in Gastric cancer HemOnc HemOnc
CapeOx Is current in Hepatocellular carcinoma HemOnc HemOnc
CapeOx Is current in Pancreatic cancer HemOnc HemOnc
CapeOx Is current in Rectal cancer HemOnc HemOnc
CapeOx Can be preceded by Colon cancer surgery HemOnc HemOnc
CapeOx Can be preceded by CAPIRI HemOnc HemOnc
CapeOx Can be preceded by Irinotecan monotherapy HemOnc HemOnc
CapeOx Can be preceded by Gastrectomy HemOnc HemOnc
CapeOx Can be preceded by Capecitabine monotherapy HemOnc HemOnc
CapeOx Can be preceded by Capecitabine and RT HemOnc HemOnc