Table 1:
Mutant name | Mutation | Specific substitutions | Corresponding mutant virus | Study |
---|---|---|---|---|
WT | Wild type; no mutations in UL138 | TB138-HA AD138 |
(Lee et al., 2015) | |
mY-1 | Mutated first tyrosine motif | Y26LAY to A26AAY | ||
mY-2 | Mutated second tyrosine motif | Y44RWL to A44AAA | ||
mY-3 | Mutated third tyrosine motif | Y54GEY to A54GEY | ||
mLL | Mutated acidic cluster dileucine motif | D142VDLL to A142AAAA | TB138 mLL-HA | |
Δ4 | All Golgi motifs mutated | The four above mutant alleles combined in a single allele | TB138 Δ4-HA AD138Δ4 |
(Gelbmann and Kalejta, 2019) |