Table 4.
Discrimination and calibration of univariate and multivariate regression models for 60-day mortality after RSV LRTI
| Model | AUC | Brier score | Pseudo-R2 |
|---|---|---|---|
| All patients | |||
| Lymphopenia | 0.62 | 0.18 | 0.04 |
| Baseline-RSI | 0.53 | 0.19 | 0.002 |
| Peak-RSI | 0.77 | 0.15 | 0.20 |
| Delta-RSI | 0.76 | 0.14 | 0.23 |
| Peak-RSI and lymphopenia | 0.78 | 0.14 | 0.21 |
| Delta-RSI and lymphopenia | 0.78 | 0.14 | 0.24 |
| HCT Recipients Only | |||
| ISI | 0.69 | 0.18 | 0.10 |
| SID Criteria | 0.73 | 0.17 | 0.15 |
| Baseline-RSI | 0.52 | 0.20 | 0.004 |
| Peak-RSI | 0.74 | 0.15 | 0.20 |
| Delta-RSI | 0.74 | 0.14 | 0.24 |
| Peak-RSI and ISI | 0.80 | 0.14 | 0.25 |
| Delta-RSI and ISI | 0.81 | 0.13 | 0.29 |
| Peak-RSI and SID | 0.83 | 0.13 | 0.30 |
| Delta-RSI and SID | 0.85 | 0.12 | 0.36 |
Abbreviation: RSV: respiratory syncytial virus; LRTI: lower respiratory tract infection; AUC: area under the receiver-operating characteristics curve; RSI: Radiologic Severity Index; HCT: hematopoietic cell transplant; ISI: Immunodeficiency Scoring Index; SID: severe immunodeficiency criteria