Skip to main content
. 2019 Aug 13;10(48):4973–4986. doi: 10.18632/oncotarget.27132

Table 3. Association between ELAC2 staining and prostate cancer phenotype in the TMPRSS2: ERG fusion positive subset.

Parameter Evaluable ELAC2 nuclear staining (%) P value
(n) Negative Weak Moderate Strong
Total 3 624 24.6 28.9 35.6 10.8
Tumor stage
pT2 2 130 25.0 29.2 35.4 10.4 0.2855
pT3a 981 22.6 29.7 36.4 11.3
pT3b 475 27.2 27.2 34.5 11.2
pT4 21 23.8 14.3 33.3 28.6
Gleason grade
≤3+3 770 33.9 27.7 30.9 7.5 <0.0001
3+4 2 064 22.4 29.1 37.4 11.1
3+4 Tert.5 110 17.3 30.9 39.1 12.7
4+3 358 23.7 28.2 35.2 12.8
4+3 Tert.5 185 17.3 29.7 39.5 13.5
≥4+4 135 24.4 32.6 29.6 13.3
Lymph node metastasis
N0 2 085 22.0 27.1 37.9 12.9 0.1541
N+ 232 22.4 33.6 31.9 12.1
Preoperative PSA level (ng/ml)
<4 496 24.4 29.0 35.5 11.1 0.9981
4–10 2 184 24.4 28.8 35.9 11.0
10–20 660 25.2 28.8 35.9 10.2
>20 234 26.1 30.3 33.3 10.3
Surgical margin
Negative 2 818 24.8 28.7 35.5 11.0 0.8555
Positive 738 24.3 30.1 35.5 10.2