Table 1.
Overall results on perturbation pattern prediction, 0.66 is the best performance of DYNAMO, 0.63 is the accuracy of distance model.
| Model Name | Correlation Score | |
|---|---|---|
| Ground truth | Biochemical | 1.00 |
| *DYNAMO5 | Propagation (signed, directed) | 0.66 |
| Propagation (directed) | 0.65 | |
| Propagation (undirected) | 0.40 | |
| Distance (directed) | 0.63 | |
| Distance (undirected) | 0.36 | |
| *Our model | Upper Bound of Bio_Impact | 0.84 |
| Upper Bound of Scaled_Impact | 0.80 | |
| Scaled_Impact Full Graph Prediction | 0.70 | |
| Scaled_Impact Sparse Graph Prediction | 0.73 |
0.70 and 0.73 are the accuracies of our proposed enhancement methods on distance model.