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. 2019 Jul 26;116(33):16551–16560. doi: 10.1073/pnas.1904885116

Fig. 8.

Fig. 8.

Schematic diagram represents that leptin signaling-dependent activation of mTORC2/Phllp1/Akt pathway abrogates lysosomal function and negatively regulates macrophage defense during S. Typhimurium infection.