Fig. 6.

Scn1a deletion in the hippocampus does not cause impairment in context-dependent fear-conditioning. Freezing behavior was recorded in AAV-ΔCre or AAV-Cre–injected Scn1a floxed mice during a series of 2-min trials before and at designated time points after a mild foot shock. Mice were habituated for 2 min in a box containing a wire floor grid, after which they received a foot shock. Freezing behavior was calculated during the 2 min habituation (pre-foot shock), training (immediately after foot shock), 30-min short-term memory (STM), 24-h long-term memory (LTM), and 7-d long-term memory trials. Blue = AAV-ΔCre, n = 15; red = AAV-Cre, n = 16. Data are represented as mean ± SEM.