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Structure–activity relationships for antibiotic activity and membrane activity
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MIC, minimum inhibitory concentration (in micrograms per milliliter); PKC, persister killing concentration (in micrograms per milliliter) required to kill 5 × 107 CFU/mL MRSA persister cells below the limit of detection; MP, membrane permeabilization (determined based on SYTOX Green fluorescence intensity); MFI, membrane fluidity increase (determined based on Laurdan GP measurement).
