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. 2019 Aug 1;116(33):16577–16582. doi: 10.1073/pnas.1900406116

Fig. 4.

Fig. 4.

Reducing nigral Sry expression in male rats alleviates toxin-induced elevation of PD pathogenesis genes. Effect of ASO (or SO) infusion on expression of nigral genes (fold-intact side) involved in DA machinery, DNA damage, oxidative stress and mitochondrial function, and inflammation at 2 d after injection of 6-OHDA (A) or rotenone (B) in male rats or injection of 6-OHDA in female rats (C) (n ≥5/group). *P < 0.05, **P < 0.01 vs. SO, unpaired t test. The dashed line represents baseline levels.