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. 2019 Aug 16;23:281. doi: 10.1186/s13054-019-2560-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — ROC curves of CRT and ∆CRT-PLR to predict CRT response to volume expansion. CRT, capillary refill time; CRT responders, response to volume expansion defined as patients showing a decrease in CRT after VE of at least 25%; PCO₂gap, central venous-to-arterial carbon dioxide difference; PLR, passive leg raising; VE, volume expansion